Simvastatin Treatment Shows No Effect on the Incidence of Cerebral Malaria or Parasitemia during Experimental Malaria
نویسندگان
چکیده
منابع مشابه
Simvastatin treatment shows no effect on the incidence of cerebral malaria or parasitemia during experimental malaria.
Statins, 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors, reduce in vitro growth of Plasmodium falciparum (5). With great interest, we read the letter of Pradines et al. reporting on a 10-fold-higher growth inhibition of P. falciparum by atorvastatin than by simvastatin, suggesting that atorvastatin be considered a candidate drug for malaria treatment (14). Apart from the cholesterol...
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ژورنال
عنوان ژورنال: Antimicrobial Agents and Chemotherapy
سال: 2008
ISSN: 0066-4804,1098-6596
DOI: 10.1128/aac.01428-07